Integrative multi-omics identifies high risk Multiple Myeloma segment associated with significant DNA loss and dysregulated DNA repair and cell cycle pathways
M. Ortiz Estevez, M. Samur, F. Towfic, E. Flynt, N. Stong, I. S. Jang, K. Wang, P. Vyas, N. Munshi, H. Avet-Loiseau, M. W. Trotter, G. J. Morgan, B. Walker, A. Thakurta
The paper identifies a high-risk Multiple Myeloma subgroup using multi-omics data, linking genomic loss to dysregulated DNA repair and cell cycle pathways.
bioRxiv · Sep 3, 2021Cancer Biology