Cancer BiologybioRxivPreprint
Multiplexed identification of RAS paralog imbalance as a driver of lung cancer growth
R. Tang, E. G. Shuldiner, M. Kelly…·M. M. Winslow
This study identifies HRAS and NRAS as suppressors of KRASG12D-driven lung cancer using CRISPR screens in mouse models and confirms their role in human cell lines.
DOI 10.1101/2021.07.08.451571