Author

E. J. Soderblom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 5 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

G. Waitt· 2 shared J.-T. A. Chi· 2 shared T. Ho· 2 shared A. J. Watson· 1 shared A. Rajab· 1 shared B. Racz· 1 shared C. S. Evans· 1 shared C.-C. Lin· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

G. Waitt

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Protein CoAlation on TXNRD2 regulates mitochondrial thioredoxin system to protect against ferroptosis

C.-C. Lin, Y.-T. Lin, S.-Y. Chen, Y. Setayeshpour, Y. Chen, D. E. Dunn, E. J. Soderblom, G. Zhang, V. Filonenko, S. Y. Jeong, S. R. Floyd, S. Hayflick, I. Gout, J.-T. A. Chi

This study identifies CoA-mediated post-translational modification of TXNRD2 as a novel mechanism regulating the mitochondrial thioredoxin system to protect against ferroptosis.

bioRxiv · May 16, 2024 · PreprintCell Biology

Presynaptic Rac1 in the hippocampus selectively regulates working memory

J. Kim, E. Bustamante, P. Sotonyi, N. Maxwell, P. Parameswaran, J. K. Kent, W. C. Wetsel, E. J. Soderblom, B. Racz, S. H. Soderling

This study shows that presynaptic Rac1 signaling selectively regulates spatial working memory, with distinct effects on synaptic vesicles and morphology compared to postsynaptic Rac1 inhibition.

bioRxiv · Mar 18, 2024Animal Behavior & Cognition

O-GlcNAcylation regulates neurofilament-light assembly and function and is perturbed by Charcot-Marie-Tooth disease mutations

D. T. Huynh, J. Hu, J. R. Schneider, K. N. Tsolova, E. J. Soderblom, A. J. Watson, J.-T. A. Chi, C. S. Evans, M. Boyce

This study shows that O-GlcNAcylation regulates NF-L assembly and function, and CMT mutations disrupt this process, linking glycosylation defects to neurodegeneration.

bioRxiv · Feb 22, 2023Cell Biology

Dataset on the mass spectrometry-based proteomic profiling of mouse embryonic fibroblasts from a wild type and DYT-TOR1A mouse model of dystonia, basally and during stress

K. Shroff, Z. F. Caffall, E. J. Soderblom, G. Waitt, T. Ho, N. Calakos

The paper presents subcellular proteomic data from wildtype and DYT-TOR1A mouse embryonic fibroblasts under basal and stress conditions to study TorsinA's role in dystonia.

bioRxiv · Jul 9, 2021Cell Biology

Genetic Disruption of WASHC4 Drives Endo-lysosomal Dysfunction and Cognitive-Movement Impairments in Mice and Humans

J. L. Courtland, T. W. Bradshaw, G. Waitt, E. J. Soderblom, T. Ho, A. Rajab, R. Vancini, I. H. Kim, S. Soderling

This study identifies a mutation in WASHC4 causing endo-lysosomal dysfunction and cognitive-movement impairments in mice and humans.

bioRxiv · Aug 6, 2020Cell Biology