Author

E. K. Silverman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Boueiz· 1 shared A. M. K. Choi· 1 shared A. Masoomi· 1 shared B. Ma· 1 shared C. G. Lee· 1 shared C. P. Hersh· 1 shared C.-M. Lee· 1 shared D. C. Yee· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

A. Boueiz

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Chitinase 3-like-1 (CHI3L1) Inhibits Innate Anti-Tumor and Tissue Remodeling ImmuneResponses by Regulating CD47-SIRPα and CD24-Siglec10-Mediated Phagocytosis

B. Ma, S. Kamle, C.-M. Lee, J. H. Lee, D. C. Yee, Z. Zhu, E. K. Silverman, D. DeMeo, A. M. K. Choi, C. G. Lee, J. A. Elias

This study shows CHI3L1 inhibits macrophage phagocytosis by modulating CD47-SIRPα and CD24-Siglec10 pathways, contributing to immune evasion in cancer and COPD.

bioRxiv · Dec 27, 2023 · PreprintImmunology

Improved Prediction of Smoking Status via Isoform-Aware RNA-seq Deep Learning Models

Z. Wang, A. Masoomi, Z. Xu, A. Boueiz, S. Lee, T. Zhao, M. Cho, C. P. Hersh, E. K. Silverman, J. Dy, P. Castaldi

The paper develops deep learning models using RNA-seq data that incorporate isoform and exon information to improve smoking status prediction, achieving higher AUC than gene-level models.

bioRxiv · Sep 9, 2020 · PreprintGenomics