The Balance between Saturated and Unsaturated Fatty Acids Regulates Ovarian Cancer Cell Fate
G. Zhao, Y. Tan, H. Cardenas, D. Vayngart, H. Huang, Y. Wang, R. Keathley, J.-J. Wei, C. R. Ferreira, J.-X. Cheng, D. Matei
This study shows that the balance between saturated and unsaturated fatty acids, regulated by SCD, affects ovarian cancer cell survival and tumor progression, with UFAs protecting against ER stress-induced apoptosis.
bioRxiv · May 24, 2022 · PreprintCancer Biology