ImmunologybioRxiv
Human neutrophil development and functionality are enabled in a humanized mouse model
Y. Zheng, E. Sefik, J. Astle…·R. A. Flavell
This study develops a humanized mouse model, MISTRGGR, that supports the generation of functional human neutrophils in circulation and tissues, which respond to inflammatory and infectious challenges.
DOI 10.1073/pnas.2121077119