An in vivo KRAS allelic series reveals distinct phenotypes of common oncogenic variants
M. P. Zafra, D. Alonso-Curbelo, S. Goswami, E. M. Schatoff, T. Han, J. E. Wilkinson, L. E. Dow
The paper creates KRAS mutant mouse models to study how different oncogenic variants affect tumor development and therapy response in vivo.
bioRxiv · Nov 20, 2019Cancer Biology