Pharmacology & ToxicologybioRxiv
Cell morphological profiling enables high-throughput screening for PROteolysis TArgeting Chimera (PROTAC) phenotypic signature
K. Moreau, M.-A. Trapotsi, E. Mouchet…·A. Bender
This study uses cell morphological profiling to identify phenotypic signatures of PROTACs, revealing mitotoxicity that cannot be predicted from individual components.