BiochemistrybioRxivPreprint
Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking
DOI 10.1101/2023.06.20.545796
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2 papers
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S. K. See, M. Chen, S. Bax…·M. Kampmann
The paper identifies PIKfyve inhibition as a strategy to block α-synuclein fibril escape from lysosomes, reducing aggregation spread in a human cell model.