Author

E. Rayner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Pathology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:non-human primate· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:spatial domain detection· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

K. A. Ryan· 4 shared K. R. Bewley· 3 shared R. Cobb· 3 shared R. J. Watson· 3 shared S. A. Fotheringham· 3 shared Y. Hall· 3 shared A. C. Marriott· 2 shared B. E. Cavell· 2 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

K. A. Ryan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Sequential delivery of LAIV and SARS-CoV-2 in the ferret model can reduce SARS-CoV-2 shedding and does not result in enhanced lung pathology.

K. A. Ryan, K. E. Schewe, J. Crowe, S. A. Fotheringham, Y. Hall, R. Humphreys, A. C. Marriott, J. Paterson, E. Rayner, F. J. Salguero, R. J. Watson, C. J. Whittaker, M. W. Carroll, O. Dibben

This study shows that administering LAIV before or after SARS-CoV-2 infection in ferrets does not worsen disease and may reduce viral shedding.

bioRxiv · Feb 1, 2021Microbiology

Immunological and pathological outcomes of SARS-CoV-2 challenge after formalin-inactivated vaccine immunisation of ferrets and rhesus macaques

K. R. Bewley, K. E. R. Gooch, K. M. Thomas, S. R. Longet, N. Wiblin, L. Hunter, K. Chan, P. Brown, R. A. Russell, C. Ho, G. Slack, H. E. Humphries, L. Alden, L. Allen, M. Aram, , M. Carroll

This study evaluates vaccine-enhanced disease in ferrets and rhesus macaques after formalin-inactivated SARS-CoV-2 vaccination, finding mild transient lung pathology but no significant enhancement.

bioRxiv · Dec 21, 2020Pathology

Prophylactic intranasal administration of a TLR2 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model

P. C. Proud, D. Tsitoura, R. J. Watson, B. Y. Chua, M. J. Aram, K. R. Bewley, B. E. Cavell, R. Cobb, S. Dowall, S. A. Fotheringham, C. M. Ho, V. Lucas, D. Ngabo, E. Rayner, K. A. Ryan, , M. W. Carroll

bioRxiv · Sep 25, 2020Immunology

Dose-dependent response to infection with SARS-CoV-2 in the ferret model: evidence of protection to re-challenge

K. A. Ryan, K. R. Bewley, S. A. Fotheringham, P. Brown, Y. Hall, A. C. Marriott, J. A. Tree, L. Allen, M. J. Aram, E. Brunt, K. R. Buttigieg, B. E. Cavell, D. P. Carter, R. Cobb, N. S. Coombes, , M Dennis

This study investigates the dose-dependent response of ferrets to SARS-CoV-2 infection, showing protection against re-challenge and mild clinical disease.

bioRxiv · May 29, 2020Microbiology

A Zika vaccine based on chimpanzee adenovirus ChAdOx1 elicits lineage-transcending sterile immunity and prevents colonisation of brain and ovaries

C. Lopez-Camacho, S. Dowall, V. Graham, S. Findlay-Wilson, E. Rayner, Y. Chan Kim, R. Hewson, A. Reyes-Sandoval

This paper evaluates a ZIKV vaccine based on chimpanzee adenovirus ChAdOx1, showing it provides sterile immunity against both Asian and African lineages and prevents viral colonization of brain and ovaries.

bioRxiv · Jan 14, 2019 · PreprintPathology