Author

E. S. Baker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Pharmacology & Toxicology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:metabolomics· 3 Assay:metagenomics· 3 Research Focus:ecology & biodiversity· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. M. Theriot· 2 shared J. N. Dodds· 2 shared M. K. Dougherty· 2 shared S. K. McGill· 2 shared S. M. Belcher· 2 shared A. Gulati· 1 shared A. K. Boatman· 1 shared A. K. Stewart· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

C. M. Theriot

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Metagenomic, metabolomic, and lipidomic shifts associated with fecal microbiota transplantation for recurrent Clostridioides difficile infection

A. S. McMillan, G. Zhang, M. K. Dougherty, S. K. McGill, A. S. Gulati, E. S. Baker, C. M. Theriot

This study examines changes in microbiome, metabolome, and lipidome after fecal microbiota transplantation for recurrent C. difficile infection, identifying lipid and bile acid shifts linked to treatment success.

bioRxiv · Feb 7, 2024 · PreprintMicrobiology

Characterizing Adeno-Associated Virus Capsids with both Denaturing and Intact Analysis Methods

J. P. Ryan, M. M. Kostelic, C.-C. Hsieh, J. B. Powers, C. A. Aspinwall, J. N. Dodds, J. E. Schiel, M. T. Marty, E. S. Baker

The paper combines two analytical methods to characterize AAV capsids and their subunits, evaluating capsid integrity and VP sequence variations across three serotypes.

Journal of the American Society for Mass Spectrometry · Nov 27, 2023Peer-reviewedBiochemistry

Assessing Per- and Polyfluoroalkyl Substances (PFAS) in Fish Fillet Using Non-Targeted Analyses

A. K. Boatman, J. R. Chappel, M. E. Polera, J. N. Dodds, S. M. Belcher, E. S. Baker

The paper assesses PFAS in fish fillets from North Carolina using non-targeted analyses, detecting 36 PFAS including 19 not found by routine methods and high PFOS levels.

bioRxiv · Sep 1, 2023Pharmacology & Toxicology

Distinct bile salt hydrolase substrate preferences dictate C. difficile pathogenesis

M. H. Foley, M. E. Walker, A. K. Stewart, S. O'Flaherty, E. C. Gentry, G. Allen, S. Patel, M. Pan, V. V. Beaty, M. E. Vanhoy, M. K. Dougherty, S. K. McGill, A. Gulati, P. Dorrestein, E. S. Baker, , C. M. Theriot

The paper identifies bile salt hydrolase (BSH) substrate preferences and shows they inhibit C. difficile by altering bile acid pools in CDI models.

bioRxiv · Mar 24, 2022 · PreprintMicrobiology

Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances

K. I. Kirkwood, J. Fleming, H. Nguyen, D. M. Reif, E. S. Baker, S. M. Belcher

This study uses pine needles and a non-targeted method to detect over 70 PFAS across six decades, revealing temporal and spatial patterns of exposure and contamination.

bioRxiv · Aug 24, 2021Pharmacology & Toxicology

A Histoplasma capsulatum lipid metabolic map identifies antifungal targets

D. Zamith-Miranda, H. M. Heyman, M. C. Burnet, S. P. Couvillion, X. Zheng, N. Munoz, W. C. Nelson, J. E. Kyle, E. M. Zink, K. K. Weitz, K. J. Bloodsworth, G. C. Clair, J. D. Zucker, J. R. Teuton, S. H. Payne, , E. S. Nakayasu

This study constructs a lipid metabolic map of Histoplasma capsulatum and identifies potential antifungal drug targets through pathway validation and compound testing.

bioRxiv · Mar 2, 2020Microbiology