E. S. Nakayasu

This paper introduces a fast and sensitive size-exclusion chromatography method for plasma extracellular vesicle proteomic analysis, demonstrating its utility in identifying EV proteins related to physical activity.

This study shows that inhibiting PERK reduces autoimmune diabetes risk in mice by decreasing β cell immunogenicity and improving islet function.

This study shows senescent cell-derived extracellular vesicles (senEVs) suppress tumor growth by coordinating immune surveillance, specifically by recruiting MHC-II+ antigen-presenting cells and activating CCR2+ TH17 cells.

This study shows lysine acetylation in E. coli inhibits translation by disrupting ribosome subunit association, linking metabolic state to protein synthesis.

This study identifies Ceg3 as an ADP-ribosyltransferase that modifies host ADP/ATP translocases, impairing their function and modulating host energy metabolism to aid Legionella pneumophila survival.

This study compares extracellular vesicles from Candida auris and Candida albicans, finding distinct molecular profiles and immune-modulating properties that may contribute to C. auris pathogenesis.

This study examines the effects of genome reduction in E. coli on proteome expression and stability of a biosynthetic pathway for pigment production, finding that proteome fraction elimination impacts fitness and bioproduction balance.

This study constructs a lipid metabolic map of Histoplasma capsulatum and identifies potential antifungal drug targets through pathway validation and compound testing.

This study shows that protein synthesis and a stringent response are required for bacterial longevity during growth arrest in Rhodopseudomonas palustris.

This paper compares multi-omics profiles of two Candida auris isolates and a Candida albicans reference strain to understand drug resistance and virulence mechanisms.

This study shows Listeria monocytogenes secretes biologically active extracellular vesicles containing virulence factors like LLO and PI-PLC, which contribute to cytotoxicity in macrophages.