Author

E. Toprak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Koh· 1 shared A. R. Atilgan· 1 shared C. Atilgan· 1 shared C. Behrendt· 1 shared H. Abdizadeh· 1 shared I. K. Gaszek· 1 shared J. Kim· 1 shared K. Reynolds· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

A. Koh

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJan 11, 2023

Susceptible bacteria survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance

M. Rodrigues, P. Sabaeifard, M. S. Yildiz…·E. Toprak

The paper shows that gut bacteria can survive antibiotic treatment without developing resistance by acquiring mutations that enhance their ability to persist and invade intestinal cells.

DOI 10.1101/2023.01.11.523617

mouseproteomics

𝕏 PostBluesky

Evolutionary BiologybioRxivAug 22, 2018

High-order epistasis in catalytic power of dihydrofolate reductase gives rise to a rugged fitness landscape in the presence of trimethoprim selection

Y. T. Tamer, I. K. Gaszek, H. Abdizadeh…·E. Toprak

The paper quantifies high-order epistasis in DHFR mutations under trimethoprim selection, revealing complex fitness landscapes and implications for inhibitor design.

DOI 10.1093/molbev/msz086

E. coliproteomics

𝕏 PostBluesky