Author

F. Aguet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

G. Getz· 4 shared A. Regev· 2 shared S. Anand· 2 shared A. Apffel· 1 shared A. D. Davidson· 1 shared A. Dutta· 1 shared A. Greka· 1 shared A. J. Dunford· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersCancer Biology

G. Getz

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genetic Subtypes of Smoldering Multiple Myeloma are associated with Distinct Pathogenic Phenotypes and Clinical Outcomes

M. Bustoros, S. Anand, R. Sklavenitis-Pistofidis, R. Redd, E. M. Boyle, B. Zhitomirsky, A. J. Dunford, Y.-T. Tai, S. J. Chavda, C. Boehner, C. J. Neuse, M. Rahmat, A. Dutta, T. Casneuf, R. Verona, , I. M. Ghobrial

This study identifies six genetic subtypes of smoldering multiple myeloma associated with distinct clinical outcomes and progression risks.

bioRxiv · Dec 10, 2021Cancer Biology

Single-nucleus cross-tissue molecular reference maps to decipher disease gene function

G. Eraslan, E. Drokhlyansky, S. Anand, A. Subramanian, E. Fiskin, M. Slyper, J. Wang, N. Van Wittenberghe, J. M. Rouhana, J. Waldman, O. Ashenberg, D. Dionne, T. S. Win, M. S. Cuoco, O. Kuksenko, , A. Regev

The paper develops a cross-tissue single-nucleus RNA-seq atlas to identify cell types and gene functions in health and disease.

bioRxiv · Jul 19, 2021Cell Biology

The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro

T. M. Yaron, B. E. Heaton, T. M. Levy, J. L. Johnson, T. X. Jordan, B. M. Cohen, A. Kerelsky, T.-Y. Lin, K. M. Liberatore, D. K. Bulaon, E. R. Kastenhuber, M. N. Mercadante, K. Shobana-Ganesh, L. He, R. E. Schwartz, , M Kavanagh-Williamson

This study identifies Alectinib as an FDA-approved drug that inhibits SARS-CoV-2 nucleocapsid phosphorylation and viral replication in vitro by targeting host kinases.

bioRxiv · Aug 14, 2020 · PreprintMicrobiology

Thousands of novel unannotated proteins expand the MHC I immunopeptidome in cancer

T. Ouspenskaia, T. Law, K. R. Clauser, S. Klaeger, S. Sarkizova, F. Aguet, B. Li, E. Christian, B. A. Knisbacher, P. M. Le, C. R. Hartigan, H. Keshishian, A. Apffel, G. Oliveira, W. Zhang, , A. Regev

The paper identifies thousands of novel unannotated proteins in cancer that contribute to the MHC I immunopeptidome, expanding potential targets for immunotherapy.

bioRxiv · Feb 12, 2020 · PreprintCancer Biology