Author

F. C. Koehler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

B. Schermer· 3 shared R.-U. Mueller· 3 shared T. Benzing· 3 shared F. Grundmann· 2 shared J.-W. Lackmann· 2 shared K. J. R. Hoyer-Allo· 2 shared M. Hoehne· 2 shared M. R. Spaeth· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersPathology

B. Schermer

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Author profile →

3 papers

Recent·Most cited

Three-dimensional Super-resolved Imaging of Paraffin-embedded Kidney Samples

D. Unnersjoe-Jess, A. Ramdedovic, M. Hoehne, L. Butt, F. C. Koehler, R.-U. Mueller, P. F. Hoyer, H. Blom, B. Schermer, T. Benzing

This paper develops protocols for three-dimensional STED and confocal imaging of FFPE kidney tissue, achieving similar staining and image quality as previous methods.

Kidney360 · Mar 31, 2022Peer-reviewedPathology

A systematic analysis of diet-induced nephroprotection reveals overlapping and conserved changes in cysteine catabolism

F. C. Koehler, C.-Y. Fu, M. R. Spaeth, K. J. R. Hoyer-Allo, K. Bohl, H. Goebel, J.-W. Lackmann, F. Grundmann, T. Osterholt, C. Gloistein, J. D. Steiner, A. Antebi, T. Benzing, B. Schermer, G. Schwarz, , R.-U. Mueller

This study compares six dietary regimens to identify their protective effects against kidney injury and finds overlapping metabolic changes in cysteine catabolism across diets.

bioRxiv · Sep 8, 2021Biochemistry

Organ protection by caloric restriction depends on activation of the de novo NAD+ synthesis pathway

M. R. Spaeth, K. J. R. Hoyer-Allo, M. Johnsen, M. Hoehne, C. Lucas, S. Brodesser, J.-W. Lackmann, K. Kiefer, F. C. Koehler, P. Schiller, T. Kubacki, F. Grundmann, T. Benzing, B. Schermer, V. Burst, R.-U. Mueller

This study identifies KYNU-dependent de novo NAD+ biosynthesis as a mechanism by which caloric restriction protects against acute kidney injury in mice and humans.

bioRxiv · Aug 20, 2021Physiology