Author

A. Antebi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 7 Physiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:cell type annotation· 5 Organism:C. elegans· 4 Research Focus:cell signaling & trafficking· 4 Research Focus:development & morphogenesis· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2

Frequent Co-Authors

R. Ripa· 4 shared C. Latza· 3 shared A. Annibal· 2 shared C. Calabrese· 2 shared E. Ballhysa· 2 shared J. Steiner· 2 shared K. Schilling· 2 shared L. Dolfi· 2 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersCell Biology

R. Ripa

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

A primordial TFEB-TGFβ signaling axis systemically regulates diapause and stem cell longevity

T. J. Nonninger, J. Mak, B. Gerisch, V. Ramponi, K. Kawamura, K. Schilling, C. Latza, J. Koelschbach, R. Ripa, M. Serrano, A. Antebi

The paper identifies a TFEB-TGFβ signaling axis that regulates diapause and stem cell longevity across species by coordinating nutrient availability with growth signals.

bioRxiv · Oct 6, 2023 · PreprintCell Biology

Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response (MERSR) and its Impact on Proteostasis

J. J. Li, N. Xin, C. Yang, L. A. Tavizon, R. Hong, J. Park, T. I. Moore, R. G. Tharyan, A. Antebi, H.-E. Kim

The paper identifies a Mitochondria to ER Stress Response (MERSR) that enhances proteostasis by modulating UPRER and PERK-eIF2 signaling in disease models.

bioRxiv · Sep 7, 2023Cell Biology

Hexokinase regulates Mondo-mediated longevity via the PPP and organellar dynamics

R. Laboy, M. Ndoci, S. S. Tabrez, M. Vonolfen, E. Ballhysa, T. Droth, K. Schilling, A. Loehrke, I. Atanassov, A. Antebi

This study identifies hexokinase isozymes as regulators of MML-1 function in C. elegans, showing their role in nuclear localization, transcriptional activity, and longevity.

bioRxiv · Jun 14, 2023 · PreprintCell Biology

Mitochondrial translocation of TFEB regulates complex I and inflammation

C. Calabrese, H. Nolte, M. R. Pitman, R. Ganesan, P. Lampe, R. Laboy, R. Ripa, J. Fischer, S. Chipurupalli, S. Gutierrez, R. Polara, D. Thomas, S. M. Pitson, A. Antebi, N. Robinson

This study shows TFEB regulates mitochondrial complex I and inflammation through non-transcriptional mechanisms, with implications for immune pathogenesis during infection.

bioRxiv · Feb 27, 2023Cell Biology

Refeeding-associated AMPKγ1 complex activity is a hallmark of health and longevity.

R. Ripa, E. Ballhysa, J. Steiner, A. Annibal, N. Hochhard, C. Latza, L. Dolfi, C. Calabrese, A. Meyer, M. C. Polidori, R.-U. Mueller, A. Antebi

This study identifies AMPKγ1 complex activity as a marker of health and longevity, showing its decline with age and association with frailty in humans and killifish.

bioRxiv · Dec 5, 2022 · PreprintPhysiology

A systematic analysis of diet-induced nephroprotection reveals overlapping and conserved changes in cysteine catabolism

F. C. Koehler, C.-Y. Fu, M. R. Spaeth, K. J. R. Hoyer-Allo, K. Bohl, H. Goebel, J.-W. Lackmann, F. Grundmann, T. Osterholt, C. Gloistein, J. D. Steiner, A. Antebi, T. Benzing, B. Schermer, G. Schwarz, , R.-U. Mueller

This study compares six dietary regimens to identify their protective effects against kidney injury and finds overlapping metabolic changes in cysteine catabolism across diets.

bioRxiv · Sep 8, 2021Biochemistry

Cell size is a determinant of stem cell potential during aging

J. Lengefeld, C.-W. Cheng, P. Maretich, M. R. McReynolds, M. Blair, H. Hagen, E. J. Sullivan, K. Majors, C. Roberts, J. H. Kang, J. Steiner, T. P. Miettinen, S. Manalis, A. Antebi, S. J. Morrison, , A. Amon

The paper shows that stem cell enlargement during aging reduces their function, and preventing this enlargement improves function.

bioRxiv · Oct 27, 2020Cell Biology

Multi-environment phenotyping of C. elegans for robust evaluation of physical performance

J. E. Hewitt, R. Laranjeiro, M. Norouzi, R. Ellwood, A. Antebi, N. J. Szewczyk, M. Driscoll, S. A. Vanapalli

This study introduces a multi-environment phenotyping approach to assess physical performance in C. elegans and evaluates drug interventions in a muscular dystrophy model.

bioRxiv · Aug 17, 2020 · PreprintPhysiology

Polyamine-controlled proliferation and protein biosynthesis are independent determinants of hair follicle stem cell fate

K. Allmeroth, C. S. Kim, A. Annibal, A. Pouikli, C. A. Chacon-Martinez, C. Latza, A. Antebi, P. Tessarz, S. A. Wickström, M. S. Denzel

This study shows polyamines regulate hair follicle stem cell fate through translation rates and N1-acetylspermidine, which increases proliferation without reducing translation.

bioRxiv · Apr 30, 2020 · PreprintCell Biology

Optimization of cryopreservation and in vitro fertilization techniques for the African turquoise killifish Nothobranchius furzeri

A. Antebi, L. Dolfi, T. K. Suen, R. Ripa

This paper develops a cryopreservation and in vitro fertilization protocol for the African turquoise killifish, achieving 40% sperm viability and ~25% fertilization rates.

bioRxiv · Apr 14, 2020Cell Biology