Dissecting the conformational complexity and flipping mechanism of a prokaryotic heme transporter
D. Wu, A. R. Mehdipour, F. Finke, H. G. Goojani, R. R. Groh, T. N. Grund, T. M. Reichhart, R. Zimmermann, S. Welsch, D. Bald, M. Shepherd, G. Hummer, S. Safarian
The paper identifies CydDC as a heme flippase essential for cytochrome bd maturation, revealing its conformational mechanism through cryo-EM and molecular dynamics.
bioRxiv · Apr 7, 2022 · PreprintMicrobiology