LIN37-DREAM Prevents DNA End Resection and Homologous Recombination at DNA Double Strand Breaks in Quiescent Cells
B.-R. Chen, Y. Wang, A. Tubbs, D. Zong, F. Fowler, N. Zolnerowich, W. Wu, A. Bennett, C.-C. Chen, W. Feng, A. Nussenzweig, J. Tyler, B. P. Sleckman
The paper shows LIN37 prevents DNA end resection and HR in quiescent cells independently of 53BP1, unlike in cycling cells.
bioRxiv · Apr 21, 2021Cell Biology