Author

B.-R. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Bennett· 1 shared A. Deshpande· 1 shared A. Ghosh· 1 shared A. J. Deshpande· 1 shared A. Nussenzweig· 1 shared A. Tubbs· 1 shared B. P. Sleckman· 1 shared C.-C. Chen· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Bennett

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Author profile →

2 papers

Recent·Most cited

LIN37-DREAM Prevents DNA End Resection and Homologous Recombination at DNA Double Strand Breaks in Quiescent Cells

B.-R. Chen, Y. Wang, A. Tubbs, D. Zong, F. Fowler, N. Zolnerowich, W. Wu, A. Bennett, C.-C. Chen, W. Feng, A. Nussenzweig, J. Tyler, B. P. Sleckman

The paper shows LIN37 prevents DNA end resection and HR in quiescent cells independently of 53BP1, unlike in cycling cells.

bioRxiv · Apr 21, 2021Cell Biology

Acute Myeloid Leukemia Driven by the CALM-AF10 Fusion Gene is Dependent on BMI1

K. Barbosa, A. Ghosh, A. Deshpande, B.-R. Chen, Y. Sun, M. Weetall, S. A. Armstrong, S. K. Bohlander, A. J. Deshpande

This study shows that BMI1 is overexpressed in CALM-AF10-positive leukemias and that inhibiting BMI1 with PTC209 or PTC596 reduces leukemia growth and prolongs survival.

bioRxiv · Jan 18, 2019Cancer Biology