Plasmacytoid dendritic cells regulate megakaryocyte and platelet homeostasis
F. Gaertner, H. Ishikawa-Ankerhold, S. Stutte, W. Fu, C. Guo, J. Weitz, A. Dueck, Z. Zhang, D. van den Heuvel, V. Fumagalli, M. Lorenz, L. von Baumgarten, K. Stark, T. Straub, S. von Stillfried, , S. Massberg
This study identifies plasmacytoid dendritic cells (pDCs) as regulators of megakaryopoiesis and platelet homeostasis, showing their role in maintaining steady-state and stress conditions, and their involvement in SARS-CoV2-induced thrombosis.
bioRxiv · May 31, 2022 · PreprintImmunology