R. Hauschild

This paper develops a 3D-ECM platform to visualize native extracellular matrix structures using cryo-FIBSEM and cryo-ET, revealing new insights into ECM composition and organization.

This study shows that amoeboid cells use nucleokinesis, a process of nuclear repositioning, to adaptively navigate heterogeneous microenvironments by reorienting between competing signals.

The paper investigates how lymph nodes accommodate size increases during immune challenges by analyzing biomechanical adaptations of fibroblastic reticular cells and fibroblasts.

This study shows how amoeboid cells use WASp-driven actin spikes to push against mechanical loads in 3D environments, enabling efficient migration through dense tissues.

This study shows that dendritic cell actin dynamics, regulated by the WAVE complex, influence T cell priming efficiency at the immunological synapse by modulating synaptic structure and adhesion.

This paper introduces 3D printed grid holders to improve cellular specimen preparation for cryo-EM by increasing reproducibility, throughput, and resource efficiency.

This study shows leukocytes can migrate without adhesion by using substrate topography to transduce force from actin retrograde flow.

This study shows that microtubules regulate protrusion retraction in migrating cells by controlling myosin II contractility through Lfc, maintaining cell shape and coherence.

The paper develops a confocal microscope setup and software for tracking moving samples, enabling long-term observation of root growth and cell migration in plants and zebrafish embryos.