A planar-polarized MYO6-DOCK7-RAC1 axis promotes tissue fluidification in mammary epithelia
L. Menin, J. Weber, S. Villa…·S. Polo
The paper identifies a MYO6-DOCK7-RAC1 axis that restricts RAC1 activity in a planar polarized manner to drive tissue fluidification and collective motion in carcinoma cell monolayers.