F. Jakab

In-depth Temporal Transcriptome Profiling of Monkeypox and Host Cells using Nanopore Sequencing

This study uses Oxford Nanopore long-read RNA-Sequencing to profile the transcriptome of monkeypox virus and host cells, revealing gene expression dynamics and host transcriptomic changes.

Isolation and genome characterization of Lloviu virus from Italian Schreibers bent-winged bats

The paper isolates and characterizes Lloviu virus from Italian bats, establishing an infectious isolate and conducting evolutionary analysis.

Methylene Blue Is a Nonspecific Protein-Protein Interaction Inhibitor with Potential for Repurposing as an Antiviral for COVID-19

This paper shows methylene blue inhibits SARS-CoV-2 spike-ACE2 interactions and viral replication, with potential as an antiviral for COVID-19.

A possible way to relate the effects of SARS-CoV-2 induced changes in transferrin to severe COVID-19 associated diseases

This study investigates how SARS-CoV-2 affects transferrin thermodynamics, suggesting it may disrupt iron metabolism and contribute to severe COVID-19 complications.

Reservoir host studies of Lloviu virus: first isolation, sequencing and serology in Schreiber's bats in Europe

This study isolates and characterizes Lloviu virus from Schreiber's bats in Europe, showing its ability to infect human and monkey cells and suggesting potential spillover risks.

Recombinant Lloviu virus as a model to study inaccessible zoonotic viruses

This study uses recombinant Lloviu virus to investigate replication mechanisms and host interactions of an uncultured filovirus related to Ebola.

Small interfering RNAs are highly effective inhibitors regarding Crimean-Congo hemorrhagic fever virus replication in vitro

This study identifies four siRNAs that effectively inhibit CCHFV replication in vitro by targeting all three viral genome segments.

The Anti-histamine Azelastine, Identified by Computational Drug Repurposing, Inhibits SARS-CoV-2 Infection in Reconstituted Human Nasal Tissue In Vitro

This paper identifies azelastine, an anti-histamine drug, as a potential inhibitor of SARS-CoV-2 infection through computational repurposing and in vitro testing in human nasal tissue.

Multiple SARS-CoV-2 introductions shaped the early outbreak in Central Eastern Europe: comparing Hungarian data to a worldwide sequence data-matrix

The paper analyzes SARS-CoV-2 genomic data from Hungary to identify multiple introduction events into Central-Eastern Europe using haplotype networks and phylogenetic analysis.