Author

S. Scott

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 7 Biophysics· 3 Plant Biology· 2 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 11 Research Focus:host-pathogen & immune response· 9 Organism:human· 4 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:ecology & biodiversity· 2 Assay:imaging· 2

Frequent Co-Authors

F. Ferrara· 3 shared N. J. Temperton· 3 shared C. J. Benham· 2 shared C. Shaheen· 2 shared D. Levens· 2 shared E. Molesti· 2 shared E. Wright· 2 shared F. Kouzine· 2 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

F. Ferrara

Mutual co-authors in cluster

Author profile →

14 papers

Recent·Most cited

Humidity determines penetrance of a latitudinal gradient in genetic selection on the microbiota by Drosophila melanogaster

C. Massey, M. E. Nosker, J. Gale, S. Scott, C. J. Walker, A. J. Cluff, S. Wilcox, A. Morrison, S. J. G. Morgan, J. Beltz, P. Schmidt, J. Chaston

This study shows that humidity influences the genetic selection on microbiota in Drosophila melanogaster, with variation in microbiota composition linked to latitude and environmental conditions.

bioRxiv · May 2, 2024 · PreprintMicrobiology

NbPTR1 confers resistance against Pseudomonas syringae pv. actinidiae in kiwifruit

S.-M. Yeh, M. Yoon, S. Scott, A. Chatterjee, L. Hemara, R. Chen, T. Wang, K. Templeton, E. Rikkerink, J. Jayaraman, C. Brendolise

This study identifies NbPTR1 as a resistance gene against Pseudomonas syringae pv. actinidiae in kiwifruit by introducing it into susceptible cultivars to confer resistance.

bioRxiv · Sep 7, 2023 · PreprintPlant Biology

Serological evidence of high pathogenicity virus infection in Eidolon helvum fruit bats in Nigeria

D. Cantoni, M. Mayora Neto, B. Auld, K. Da Costa, J. Del Rosario, V. O. Ameh, C. T. Sabeta, M. Derveni, A. Hamlet, E. Wright, S. Scott, E. S. Giotis, A. Banyard, N. J. Temperton

The study detects neutralizing antibodies against henipavirus, Nipah virus, and bat influenza in Eidolon helvum bats in Nigeria, suggesting a potential zoonotic spillover risk.

bioRxiv · Jun 14, 2023 · PreprintMicrobiology

Herbarium specimens as tools for exploring the evolution of biosynthetic pathways to fatty acid-derived natural products in plants

E. Fitzgibbons, J. Lastovich, S. Scott, A. L. Grusz, L. Busta

This study uses herbarium specimens to analyze fatty acid-derived natural products in plants and finds whole genome duplication likely drove the evolution of two chemical pathways in monocots.

bioRxiv · May 8, 2023 · PreprintPlant Biology

Assessment of pre-clinical liver models based on their ability to predict the liver-tropism of AAV vectors

A. Westhaus, M. Cabanes-Creus, K. L. Dilworth, E. Zhu, D. Salas Gomez, R. G. Navarro, A. K. Amaya, S. Scott, M. Kwiatek, A. L. McCorkindale, T. E. Hayman, S. Frahm, D. P. Perocheau, B. M. Tran, E. Vincan, , L. Lisowski

This study evaluates six AAV vectors in twelve preclinical liver models to identify the most predictive for AAV capsid selection in human hepatocyte transgene delivery.

bioRxiv · Sep 28, 2022 · PreprintBioengineering

Immunological imprinting of humoral immunity to SARS-CoV-2 in children

A. C. Dowell, T. Lancaster, R. Bruton, G. Ireland, C. Bentley, P. Sylla, J. Zuo, S. Scott, A. Jardin, J. Begum, T. Roberts, C. Stephens, S. Ditta, R. Shepherdson, A. Powell, , P. Moss

This study examines immune responses to Omicron variants in children, finding weak initial antibody responses that improve with reinfection or vaccination, while cellular immunity remains robust across all groups.

bioRxiv · Jul 26, 2022Immunology

SARS-CoV-2 evolution and patient immunological history shape the breadth and potency of antibody-mediated immunity

M. Manali, L. A. Bissett, J. Amat, N. Logan, S. Scott, E. Hughes, W. Harvey, R. Orton, E. Thomson, R. Gunson, M. Viana, B. Willett, P. R. Murcia

The paper examines how SARS-CoV-2 evolution and patient immunological history influence antibody breadth and potency against different variants.

bioRxiv · May 6, 2022Microbiology

Reservoir host studies of Lloviu virus: first isolation, sequencing and serology in Schreiber's bats in Europe

G. Kemenesi, G. E. Toth, M. Mayora-Neto, S. Scott, N. Temperton, E. Wright, E. Muhlberger, A. J. Hume, B. Zana, S. A. Boldogh, T. Gorfol, P. Estok, Z. Lanszki, B. A. Somogyi, A. Nagy, , F. Jakab

This study isolates and characterizes Lloviu virus from Schreiber's bats in Europe, showing its ability to infect human and monkey cells and suggesting potential spillover risks.

bioRxiv · Aug 10, 2021Microbiology

Power series method for solving TASEP-based models of mRNA translation

S. Scott, J. Szavits-Nossan

The paper develops a power series method to solve TASEP-based models of mRNA translation and applies it to yeast, showing agreement with simulations and supporting new hypotheses about translation dynamics.

bioRxiv · Jun 30, 2019Biophysics

Single-molecule visualization of the effects of ionic strength and crowding on structure-mediated interactions in supercoiled DNA molecules

S. Scott, C. Shaheen, B. McGuinness, K. Metera, F. Kouzine, D. Levens, C. J. Benham, S. Leslie

The paper uses single-molecule CLiC microscopy to study how ionic strength and crowding affect DNA unwinding and probe binding in supercoiled DNA molecules.

bioRxiv · Mar 28, 2019Biophysics

The bat influenza H17N10 can be neutralized by broadly-neutralizing monoclonal antibodies and its neuraminidase can facilitate viral egress.

G. Carnell, E. Giotis, K. Grehan, F. Ferrara, S. Mather, E. Molesti, S. Scott, A. Pessi, K. Lacek, N. Temperton

This paper shows that bat influenza H17N10 can be neutralized by human antibodies and its neuraminidase N10 aids viral release without using sialic acid as a receptor.

bioRxiv · Jan 12, 2019 · PreprintMicrobiology

Development and use of Lentiviral Vectors Pseudotyped with Influenza B Haemagglutinins: application to vaccine immunogenicity, mAb potency and sero-surveillance studies

F. Ferrara, G. Carnell, R. Kinsley, E. Bottcher-Friebertshauser, S. Pohlmann, S. Scott, S. Fereidouni, D. Corti, P. Kellam, S. Gilbert, N. J. Temperton

The paper develops influenza B haemagglutinin-pseudotyped lentiviral vectors as sensitive tools for detecting neutralizing and cross-reactive antibodies in vaccine and sero-surveillance studies.

bioRxiv · Dec 10, 2018 · PreprintMicrobiology

Visualizing structure-mediated interactions in supercoiled DNA molecules

S. Scott, Z. M. Xu, F. Kouzine, D. J. Berard, C. Shaheen, B. Gravel, L. Saunders, A. Hofkirchner, C. Leroux, J. Laurin, D. Levens, C. J. Benham, S. R. Leslie

The paper visualizes how DNA supercoiling and temperature affect probe binding to an unwinding site using CLiC imaging, showing increased binding with higher temperature and negative supercoiling.

bioRxiv · Mar 28, 2018Biophysics

The use of hyperimmune chicken reference sera is not appropriate for the validation of influenza pseudotype neutralization assays

F. Ferrara, E. Molesti, S. Scott, G. Cattoli, N. J. Temperton

This study shows that hyperimmune chicken reference sera are not suitable for validating influenza pseudotype neutralization assays due to unexplained cross-reactivity.

bioRxiv · Aug 23, 2017Microbiology