E. Wright

Inhibition of NFAT promotes loss of tissue resident uterine natural killer cells and attendant pregnancy complications in humans

The paper identifies NFAT inhibition as a cause of reduced uterine natural killer (uNK) cells and pregnancy complications in humans through analysis of uterus transplant recipients.

Sequential Transcriptional Programs of Tissue Residency Drive Human Uterine NK Cell Development

This study identifies sequential transcriptional programs of tissue residency driving human uterine NK cell development through single-cell analyses.

Serological evidence of high pathogenicity virus infection in Eidolon helvum fruit bats in Nigeria

The study detects neutralizing antibodies against henipavirus, Nipah virus, and bat influenza in Eidolon helvum bats in Nigeria, suggesting a potential zoonotic spillover risk.

Application and comparison of lyophilisation protocols to enhance stable long-term storage of filovirus pseudotypes for use in antibody neutralisation tests

This study compares lyophilisation protocols for filovirus pseudotypes, finding that proper lyophilisation maintains stability and functionality for neutralisation assays even at high temperatures.

SARS-CoV-2 variants of concern Alpha, Beta, Gamma and Delta have extended ACE2 receptor host-ranges

The paper examines whether SARS-CoV-2 variants Alpha, Beta, Gamma, and Delta have altered ACE2 receptor usage across different mammalian species, finding that N501Y and E484K substitutions in the Spike RBD expand their host range.

Effect of SFX-01 on proliferation of human glioblastoma cell lines

This study evaluates SFX-01's effect on glioblastoma cell proliferation, showing it inhibits growth in both monolayer and spheroid models, with IC50 values similar to reference SFN.

Reservoir host studies of Lloviu virus: first isolation, sequencing and serology in Schreiber's bats in Europe

This study isolates and characterizes Lloviu virus from Schreiber's bats in Europe, showing its ability to infect human and monkey cells and suggesting potential spillover risks.

Accelerating Prediction of Chemical Shift of Protein Structures on GPUs

The paper accelerates chemical shift prediction for large protein complexes using GPU acceleration, reducing computation time from 14 hours to 46.71 seconds.

Isolation of an antimicrobial resistant, biofilm forming, Klebsiella grimontii isolate from a re-usable water bottle.

The paper isolates a Klebsiella grimontii strain from a re-usable water bottle, identifies its antimicrobial resistance and biofilm-forming capabilities, and highlights hygiene concerns for reusable bottles.

Genome-Wide Fitness Analyses of the Foodborne Pathogen Campylobacter jejuni in In Vitro and In Vivo Models

This study identifies genes essential for Campylobacter jejuni growth and survival across multiple in vitro and in vivo conditions using transposon sequencing.