Author

S. Ross

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Cell Biology· 1 Ecology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:drug response / drug discovery· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Kalinousky· 2 shared C. Ott· 2 shared C. Shamul· 2 shared N. Parashurama· 2 shared O. Ogoke· 2 shared A. A. Wilson· 1 shared A. Alejandro Suarez-Bonnet· 1 shared A. Bardelli· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBioengineering

A. Kalinousky

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Distinct T Cell Receptor (TCR) gene segment usage and MHC-restriction between foetal and adult thymus

J. Rowell, C.-I. Lau, S. Ross, D. C. Yanez, O. Pena, B. Chain, T. Crompton

This study compares TCR gene segment usage and MHC-restriction in fetal and adult mouse thymocytes, finding distinct repertoire characteristics in fetal thymus.

bioRxiv · Sep 20, 2023Immunology

Linking collective migration/growth to differentiation boosts global shaping of the transcriptome and exhibits a grasshopper effect for driving maturation

O. Ogoke, D. Guiggey, A. Chiang, S. Thompson, T. H. A. Nguyen, D. Berke, C. Ott, A. Kalinousky, C. Shamul, P. Chen, S. Ross, Z. Chen, P. Srivastava, C. Gaughan, S. D. Mahajan, , N. Parashurama

The paper links collective migration to differentiation in hPSC-derived hepatocytes, showing a significant increase in maturation through a deep-learning gene circuit.

bioRxiv · Jul 24, 2022 · PreprintBioengineering

Bcl-xL is a key mediator of apoptosis following KRASG12C inhibition in KRASG12C mutant colorectal cancer.

H. Khawaja, R. Briggs, C. Latimer, M. Rassel, D. Griffin, L. Hanson, A. Bardelli, F. Di Nicolantonio, S. S. McDade, C. J. Scott, S. Lambe, M. Maurya, A. U. Lindner, J. H. M. Prehn, J. Sousa, , S. Van Schaeybroeck

This study identifies Bcl-xL as a mediator of resistance to KRASG12C inhibitors in colorectal cancer and shows that combining Bcl-xL inhibition with KRASG12C inhibition enhances apoptosis and reduces tumor growth.

bioRxiv · May 10, 2022Cancer Biology

Recombinant Lloviu virus as a model to study inaccessible zoonotic viruses

A. J. Hume, B. Heiden, J. Olejnik, E. L. Suder, S. Ross, W. A. Scoon, E. Bullitt, M. Ericsson, M. R. White, J. Turcinovic, T. T. N. Thao, R. M. Hekman, J. E. Kaserman, J. Huang, K. Alysandratos, , E. Mühlberger

This study uses recombinant Lloviu virus to investigate replication mechanisms and host interactions of an uncultured filovirus related to Ebola.

bioRxiv · Aug 2, 2021 · PreprintMicrobiology

Resource selection by the Endangered Arabian tahr: identifying critical habitats for conservation and climate change adaptation.

S. Ross, H. Al Rawahi, M. H. Al Jahdhami

This study identifies critical habitats for Arabian tahr by analyzing habitat selection patterns using GPS collars and resource selection functions, highlighting the importance of thermal refuges and elevation for conservation.

bioRxiv · Jan 26, 2021 · PreprintEcology

Txikispora philomaios n. sp., n. g., a Micro-Eukaryotic Pathogen of Amphipods, Reveals Parasitism and Hidden Diversity in Class Filasterea

A. Urrutia, K. Mitsi, R. Foster, S. Ross, M. Carr, I. Marigomez, M. M. Leger, I. Ruiz-Trillo, S. W. Feist, D. Bass

This study identifies a new parasitic micro-eukaryote in amphipods, describes its morphology and phylogeny, and expands known Filasterea diversity through environmental metagenomics.

bioRxiv · Jan 19, 2021Pathology

An immunogenic model of KRAS-mutant lung cancer for study of targeted therapy and immunotherapy combinations

J. Boumelha, S. de Carne Trecesson, E. Law, P. Romero-Clavijo, M. Coelho, K. Ng, E. Mugarza, C. Moore, S. Rana, D. Caswell, M. Murillo, D. Hancock, P. Argyris, W. Brown, C. Durfee, , J. Downward

This paper develops an immunogenic mouse model of KRAS-mutant lung cancer that responds to immunotherapy and reveals immune responses target endogenous retroviral antigens rather than neoantigens.

bioRxiv · Dec 22, 2020Cancer Biology

Mesenchyme modulates three-dimensional, collective cell migration of liver cells in vitro - a role for TGFβ pathway

O. Ogoke, O. Yousef, C. Ott, A. Kalinousky, L. Wayne, C. Shamul, S. Ross, N. Parashurama

This study develops 3D in vitro models of liver organogenesis to study collective cell migration, showing that mesenchyme modulates migration through TGFβ signaling and branching morphogenesis.

bioRxiv · Sep 27, 2020 · PreprintCell Biology