F. Nosten

Identification of Southeast Asian Anopheles mosquito species using MALDI-TOF mass spectrometry

This paper develops and validates a MALDI-TOF MS reference database for identifying Southeast Asian Anopheles mosquito species, achieving high accuracy with molecular validation.

Transmission-blocking activity of artesunate, chloroquine and methylene blue on Plasmodium vivax gametocytes.

This study evaluates the transmission-blocking effects of artesunate, chloroquine, and methylene blue on Plasmodium vivax gametocytes, finding that only artesunate and methylene blue significantly reduce oocyst and sporozoite development.

Plasmodium falciparum K13 mutations in Africa and Asia present varying degrees of artemisinin resistance and an elevated fitness cost in African parasites

P. falciparum K13 mutations present varying degrees of artemisinin resistance and reduced fitness in African parasites

This study examines K13 mutations in Plasmodium falciparum, showing varying degrees of artemisinin resistance and fitness costs in African parasites, while finding no significant impact on ART susceptibility in Southeast Asian strains.

Reverse transcription quantitative PCR to detect low density malaria infections

This study evaluates a qRT-PCR method for detecting low density malaria infections with reduced sample volume compared to uPCR, showing improved sensitivity and specificity in a Myanmar cohort.

Novel differential linear B-cell epitopes to identify Zika and dengue virus infections in patients

The paper identifies differential linear B-cell epitopes to distinguish Zika and Dengue virus infections, showing high sensitivity and specificity in patient samples.

Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle

The paper identifies genetic determinants of Plasmodium falciparum fitness across its life cycle using bulk segregant analysis and experimental crosses.