A. Vaughan

Dynamics of Reactive Oxygen Species and Nitrogen Cycling in Soils as a Mechanism for Volatile Reactive Nitrogen Oxide Production

The paper investigates how reactive oxygen species (ROS) from soil microbes influence volatile reactive nitrogen oxide (NOy) production, showing increased NOy emissions with higher abundance of ammonia-oxidising and denitrifying taxa.

Fecal microbial transfer and complex carbohydrates mediate protection against COPD

This study shows that fecal microbial transfer and complex carbohydrates can reduce COPD symptoms in mice and humans, linking gut microbiota to disease progression.

Airway secretory cell-derived p63+ progenitors contribute to alveolar regeneration after sterile lung injury

Reconciling the potentially irreconcilable? Genotypic and phenotypic amoxicillin-clavulanate resistance in Escherichia coli

This study shows that amoxicillin-clavulanate resistance in E. coli is quantitative, not binary, and that WGS-based predictions outperform traditional phenotyping methods.

Metagenomic Nanopore sequencing of influenza virus direct from clinical respiratory samples

This study uses metagenomic Nanopore sequencing to detect influenza virus in clinical respiratory samples, achieving high sensitivity and complete genome sequencing.

Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle

The paper identifies genetic determinants of Plasmodium falciparum fitness across its life cycle using bulk segregant analysis and experimental crosses.

Nanopore metagenomic sequencing of full length human metapneumovirus (HMPV) within a unique sub-lineage

This study uses Nanopore metagenomic sequencing to directly sequence the full-length HMPV genome from a UK patient, identifying a unique genetic group and demonstrating the utility of Nanopore for clinical diagnosis.

Klebsiella quasipneumonaiae provides a window into carbapenemase gene transfer, plasmid rearrangements and nosocomial acquisition from the hospital environment

The paper tracks K. quasipneumoniae's acquisition of carbapenemase plasmids and environmental persistence in a hospital setting over multiple years.