MicrobiologyeLifePeer-reviewed
Plasmodium falciparum K13 mutations in Africa and Asia present varying degrees of artemisinin resistance and an elevated fitness cost in African parasites
DOI 10.7554/elife.66277
Author
B. H. Stokes
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2021 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 papers
Recent·Most cited
- PhysiologybioRxivPreprint
P. falciparum K13 mutations present varying degrees of artemisinin resistance and reduced fitness in African parasites
B. H. Stokes, K. Rubiano, S. K. Dhingra…·D. A. Fidock
This study examines K13 mutations in Plasmodium falciparum, showing varying degrees of artemisinin resistance and fitness costs in African parasites, while finding no significant impact on ART susceptibility in Southeast Asian strains.
DOI 10.1101/2021.01.27.428390 - MicrobiologymBioPeer-reviewed
Plasmodium berghei K13 Mutations Mediate In Vivo Artemisinin Resistance That is Reversed by Proteasome Inhibition
N. V. Simwela, B. H. Stokes, D. Aghabi…·A. P. Waters
This study introduces K13 mutations into Plasmodium berghei to demonstrate their role in mediating artemisinin resistance in vivo, showing delayed parasite clearance and synergistic effects with proteasome inhibitors.
DOI 10.1128/mbio.02312-20 - Cell BiologybioRxiv
The antimalarial natural product salinipostin A identifies essential α/β serine hydrolases involved in lipid metabolism in P. falciparum parasites
E. Yoo, C. J. Schulze, B. H. Stokes…·M. Bogyo
The study identifies essential α/β serine hydrolases in P. falciparum as targets of the antimalarial Salinipostin A, which disrupt lipid metabolism and inhibit parasite growth.
DOI 10.1016/j.chembiol.2020.01.001