The ANKS3/BICC1 protein complex is a master post-transcriptional regulator of NPHP1 ciliopathy gene transcripts
A. Mahuzier, G. Odye, V. Grampa, A. A. Bizet, A. Viau, R. Ryan, M. Mehraz, T. Blisnick, E. Clark, C. Henry, R. Piedagnel, F. Silbermann, G. Hayot, L. De grande, A. Kahn, , S. Saunier
The paper identifies ANKS3/BICC1 as a post-transcriptional regulator of NPHP1 transcripts, linking it to ciliopathy phenotypes through transcript decay and ciliary dysfunction.
bioRxiv · Apr 18, 2024 · PreprintPathology