Author

R. Ryan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Organism:chicken / avian· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

A. A. Bizet· 1 shared A. Benmerah· 1 shared A. Kahn· 1 shared A. Loukas· 1 shared A. Mahuzier· 1 shared A. Reese· 1 shared A. Viau· 1 shared A. W. Sailer· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperPathology

A. A. Bizet

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The ANKS3/BICC1 protein complex is a master post-transcriptional regulator of NPHP1 ciliopathy gene transcripts

A. Mahuzier, G. Odye, V. Grampa, A. A. Bizet, A. Viau, R. Ryan, M. Mehraz, T. Blisnick, E. Clark, C. Henry, R. Piedagnel, F. Silbermann, G. Hayot, L. De grande, A. Kahn, , S. Saunier

The paper identifies ANKS3/BICC1 as a post-transcriptional regulator of NPHP1 transcripts, linking it to ciliopathy phenotypes through transcript decay and ciliary dysfunction.

bioRxiv · Apr 18, 2024 · PreprintPathology

Novel mechanism of MYC deregulation in Multiple Myeloma

M. Rahmat, K. Clement, J.-B. Alberge, R. Sklavenitis-Pistofidis, R. Kodgule, C. Fulco, D. Heilpern-Mallory, K. Nilsson, D. Dorfman, J. Engreitz, G. Getz, L. Pinello, R. Ryan, I. M. Ghobrial

The paper identifies a new epigenetic mechanism of MYC deregulation in multiple myeloma through enhancer accessibility and transcription factor binding, independent of translocations or amplifications.

bioRxiv · May 19, 2023 · PreprintCancer Biology

Parallel signatures of mammalian domestication and human industrialization in the gut microbiota

A. Reese, K. S. Chadaideh, C. E. Diggins, M. Beckel, P. Callahan, R. Ryan, M. Emery Thompson, R. N. Carmody

The paper compares gut microbiota changes in domesticated mammals and humans, finding diet-driven shifts in both domestic animals and industrialized humans.

bioRxiv · Apr 18, 2019Microbiology

Hookworm-derived small molecule extracts suppress pathology in a mouse model of colitis and inhibit secretion of key inflammatory cytokines in primary human leukocytes

P. Wangchuk, C. Constantinoiu, K. A. Kouremenos, L. Becker, L. Jones, C. Shepherd, G. Buitrago, P. Giacomin, N. L. Daly, M. J. McConville, R. Ryan, J. Miles, A. Loukas

This study identifies anti-inflammatory small molecules from hookworms that reduce colitis pathology in mice and inhibit cytokine secretion in human leukocytes.

Infection and Immunity · Apr 1, 2019Peer-reviewedMicrobiology