Author

S. Jean

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Immunology· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:Drosophila· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. A. Upadhyay· 2 shared G. K. Tharp· 2 shared J. Cohen· 2 shared M. Henne· 2 shared M.-F. Bossanyi· 2 shared R. Ugrankar· 2 shared T. H. Vanderford· 2 shared A. Ericsen· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

A. A. Upadhyay

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Snazarus and its human ortholog SNX25 regulate autophagic flux by affecting VAMP8 endocytosis

A. Lauzier, M.-F. Bossanyi, R. Ugrankar, M. Henne, S. Jean

The paper identifies Snazarus and SNX25 as regulators of autophagic flux by affecting VAMP8 endocytosis, with conserved roles in Drosophila and human cells.

bioRxiv · Apr 8, 2021 · PreprintCell Biology

The last battle of Anne of Brittany: solving mass grave through an interdisciplinary approach (paleopathology, anthropobiology, history, multiple isotopes and radiocarbon dating)

R. Colleter, C. Bataille, S. Milano, H. Dabernat, M. Trost, M. Marchal, C. Guilbeau-Frugier, D. Pichot, P. Hamon, F. Labaune-Jean, S. Jean, G. Le Cloirec, S. Steinbrenner, S. Duchesne, N. Telmon, , K. Jaouen

This study identifies individuals in two Breton mass graves using interdisciplinary methods, revealing they were soldiers from opposing armies during the 1491 siege of Rennes.

bioRxiv · Feb 22, 2021Ecology

The early endosomal protein Rab21 is critical for enterocyte functions and intestinal homeostasis

S. Nassari, D. Levesque, F.-M. Boisvert, S. Jean

This study shows Rab21 is essential for enterocyte function and intestinal homeostasis in Drosophila, with loss of Rab21 causing morphological defects, increased cell death, and inflammation.

bioRxiv · Nov 18, 2020 · PreprintCell Biology

Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

T. N. Hoang, M. Pino, A. K. Boddapati, E. G. Viox, C. E. Starke, A. A. Upadhyay, S. Gumber, K. Busman-Sahay, Z. Strongin, J. L. Harper, G. K. Tharp, K. L. Pellegrini, S. Kirejczyk, K. Zandi, S. Tao, , Bosinger

This study shows baricitinib reduces lung inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques without affecting viral shedding or immune responses.

bioRxiv · Sep 16, 2020Immunology

Proteomic-based evaluation of nuclear transport of NLS-tagged trastuzumab-emtansine with enhanced cytotoxic potency.

V. Lacasse, S. Beaudoin, S. Jean, J. Leyton

The paper evaluates the nuclear transport of NLS-tagged trastuzumab-emtansine using proteomic methods and identifies importin 7 as a key NTR for its cytotoxic effect.

bioRxiv · Sep 26, 2019 · PreprintCell Biology

Microbiome Stability with Chronic SIV Infection in AIDS-resistant Sooty Mangabeys

R. M. Bochart, G. K. Tharp, S. Jean, A. A. Upadhyay, M. M. Crane, T. H. Vanderford, A. M. Ortiz, A. Ericsen, J. Cohen, S. E. Bosinger

This study compares the gut microbiota stability in SIV-infected sooty mangabeys and rhesus macaques, finding that SMs maintain microbiota stability while RMs show community divergence.

bioRxiv · Sep 24, 2019 · PreprintImmunology

Drosophila Snazarus regulates a lipid droplet population at plasma membrane-droplet contacts in adipocytes

R. Ugrankar, J. Bowerman, H. Hariri, M. Chandra, K. Chen, M.-F. Bossanyi, S. Datta, S. Rogers, K. Eckert, G. Vale, A. Victoria, J. Fresquez, J. McDonald, S. Jean, B. Collins, M. Henne

This study identifies Snazarus as a regulator of lipid droplet organization in Drosophila adipocytes, showing its role in maintaining peripheral lipid droplets at plasma membrane contacts.

bioRxiv · Apr 26, 2019Cell Biology