G. B. Melikyan

Rolosense detects SARS-CoV-2 using a DNA-based motor that stalls in the presence of viral particles, offering a rapid, low-cost, point-of-care diagnostic method.

The paper shows that conformational changes in arenavirus glycoproteins trigger virion membrane permeabilization and acidification before fusion, suggesting a viroporin-like activity that aids viral entry.

This study investigates the role of human LAMP1 in LASV fusion, showing it accelerates pore formation but only modestly increases infection, with enhanced pore dilation when fusion is forced at the plasma membrane.

This study shows IFITM3 inhibits viral fusion by altering membrane curvature and stiffness, with its amphipathic helix playing a key role in these effects.