Phenotypic and functional characterisation of first trimester human placental macrophages, Hofbauer cells.
J. Thomas, A. Appios, X. X. Zhao, R. A. Dutkiewicz, M. J. Donde, C. Lee, P. M. Naidu, C. Lee, J. Cerveira, B. Liu, F. Ginhoux, G. Burton, R. S. Hamilton, A. Moffett, A. Sharkey, N. McGovern
The paper characterizes first trimester human placental macrophages, identifying Hofbauer cells as HLA-DR-FOLR2+ macrophages with microbicidal properties and secreted factors influencing placental angiogenesis.
bioRxiv · Sep 3, 2020Immunology