Author

A. Appios

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Moffett· 2 shared A. Sharkey· 2 shared N. McGovern· 2 shared R. S. Hamilton· 2 shared X. X. Zhao· 2 shared A. Vallejo· 1 shared B. Liu· 1 shared C. L. Bennett· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. Moffett

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Convergent evolution of monocyte differentiation in adult skin instructs Langerhans cell identity

A. Appios, J. Davies, S. Sirvent, S. Henderson, S. Trzebanski, J. Schroth, M. L. Law, I. Boal Carvalho, H. Yuan-Hao Kan, S. Lovlekar, C. Major, A. Vallejo, N. J. Hall, M. Ardern-Jones, S. M. Henson, , C. L. Bennett

The paper investigates how monocyte differentiation in adult skin leads to Langerhans cell identity through intrinsic and extrinsic factors.

bioRxiv · Nov 13, 2023Immunology

Human HLFneg placental erythro-myeloid progenitors give rise to HLA Class IIneg Hofbauer cells

J. R. Thomas, A. Appios, E. F. Calderbank, X. X. Zhao, R. S. Hamilton, A. Moffett, A. Sharkey, E. Laurenti, N. McGovern

The paper identifies placental erythro-myeloid progenitors (PEMPs) that generate Hofbauer cells, showing human primitive haematopoiesis occurs in the placenta, not just the yolk sac.

bioRxiv · Feb 26, 2022 · PreprintImmunology

Phenotypic and functional characterisation of first trimester human placental macrophages, Hofbauer cells.

J. Thomas, A. Appios, X. X. Zhao, R. A. Dutkiewicz, M. J. Donde, C. Lee, P. M. Naidu, C. Lee, J. Cerveira, B. Liu, F. Ginhoux, G. Burton, R. S. Hamilton, A. Moffett, A. Sharkey, N. McGovern

The paper characterizes first trimester human placental macrophages, identifying Hofbauer cells as HLA-DR-FOLR2+ macrophages with microbicidal properties and secreted factors influencing placental angiogenesis.

bioRxiv · Sep 3, 2020Immunology