A robust closed-tube method for resolving tp53M214K genotypes
The paper develops a closed-tube genotyping method for tp53M214K zebrafish mutants using HRMA and wildtype spike-in to improve speed and reliability.
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3 papers
Recent·Most cited
The paper develops a closed-tube genotyping method for tp53M214K zebrafish mutants using HRMA and wildtype spike-in to improve speed and reliability.
S. Watson, C. LaVigne, L. Xu…·G. C. Kendall
This study identifies VGLL2-NCOA2 as an oncogene driving pediatric sarcomagenesis by reactivating developmental programs, with ARF6 overexpression as a potential therapeutic target.
S. Watson, G. C. Kendall, D. Rakheja…·J. F. Amatruda
This study establishes a zebrafish model of CIC-DUX4 sarcoma, showing that CIC-DUX4 drives tumor development and that Etv4 is critical for its oncogenic effects.