GLUD1 dictates muscle stem cell differentiation by controlling mitochondrial glutamate levels
I. Soro-Arnaiz, S. Cherkaoui, G. Fitzgerald, J. Zhang, P. Gilardoni, A. Gosh, O. Bar-Nur, E. Masschelein, P. Maechler, N. Zamboni, M. Poms, A. Cremonesi, J. C. Garcia-Canaveras, K. De Bock, R. J. Morscher
This study shows that GLUD1 controls muscle stem cell differentiation by regulating mitochondrial glutamate levels and the malate-aspartate shuttle.
bioRxiv · Oct 4, 2023 · PreprintCell Biology