Author

G. Friedlander

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Y. Levin· 2 shared A. Aharonov· 1 shared A. Cachia· 1 shared A. Pavlovski· 1 shared A. Savidor· 1 shared A. Savina· 1 shared A. Shakked· 1 shared A. Shenoy· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCell Biology

Y. Levin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Chemoresistome Mapping in Individual Breast Cancer Patients Unravels Diversity in Dynamic Transcriptional Adaptation

M. Dadiani, G. Friedlander, G. Perry, N. Balint-Lahat, S. Gilad, D. Morzaev-Sulzbach, N. Bossel Ben-Moshe, A. Pavlovski, E. Domany, A. Shenoy, I. Barshack, T. Geiger, B. Kaufman, E. N. Gal-Yam

The paper maps chemoresistome dynamics in breast cancer patients to identify patient-specific resistance mechanisms and vulnerabilities.

bioRxiv · Feb 9, 2023Cancer Biology

Redifferentiated cardiomyocytes retain residual dedifferentiation signatures and are protected against ischaemic injury

A. Shakked, Z. Petrover, A. Aharonov, M. Ghiringhelli, K.-B. Umansky, P. D. Nguyen, D. Kain, J. Elkahal, Y. Divinsky, S. Miyara, G. Friedlander, A. Savidor, L. Zhang, D. Perez, N. Kastan, , E. Tzahor

This study investigates the redifferentiation process in adult mouse hearts after dedifferentiation, finding residual dedifferentiation signatures and protective effects against ischemic injury.

bioRxiv · Feb 22, 2022 · PreprintCell Biology

Epidermal stem cell compartment remains unaffected through aging in naked mole-rats.

A. Savina, T. Jaffredo, F. Saldmann, C. G. Faulkes, P. Moguelet, C. Leroy, D. Del Marmol, P. Codogno, L. Foucher, M. Viltard, G. Friedlander, S. Aractingi, R. H. Fontaine

This study shows that epidermal stem cell compartments and differentiation processes remain unchanged in naked mole-rats during aging, correlating with preserved skin healing.

bioRxiv · Nov 13, 2020Cell Biology

Inhibition of the replication of SARS-CoV-2 in human cells by the FDA-approved drug chlorpromazine

M. Plaze, D. Attali, M. Prot, A.-C. Petit, M. Blatzer, F. Vinckier, L. Levillayer, F. Perin-Dureau, A. Cachia, G. Friedlander, F. Chretien, E. Simon-Loriere, R. Gaillard

This study tests chlorpromazine's antiviral effect on SARS-CoV-2 in human and monkey cells, finding an IC50 of ~10M and suggesting its potential repurposing for COVID-19 treatment.

bioRxiv · May 5, 2020Microbiology

CSNAP, the smallest CSN subunit, modulates proteostasis through cullin-RING ubiquitin ligases

M. G. Füzesi-Levi, R. I. Enchev, G. Ben-Nissan, Y. Levin, M. Kupervaser, G. Friedlander, T. M. Salame, R. Nevo, M. Peter, M. Sharon

This study identifies CSNAP as a key subunit of the CSN complex that modulates CRL activity through steric inhibition, affecting cell viability and DNA damage response.

bioRxiv · Oct 2, 2018Biochemistry