Author

G. G. Tall

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Assay:cryo-EM· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. V. Smrcka· 1 shared A. Wohlkonig· 1 shared C. J. Thomas· 1 shared C. Yates-Hansen· 1 shared I. Fisher· 1 shared J. E. Burke· 1 shared J. Johnston· 1 shared J. Steyaert· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. V. Smrcka

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJan 4, 2020

Crystal and cryo-EM structures of the cytosolic G protein alpha chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1

L. J. McClelland, K. Zhang, T.-C. Mou…·S. R. Sprang

This study reports the crystal and cryo-EM structures of Ric-8A bound to Gαi1, revealing its mechanism of GTP exchange and chaperone activity through structural interactions.

DOI 10.1101/2020.01.04.893156

cryo-EMprotein structure

𝕏 PostBluesky

BiochemistrybioRxivOct 18, 2019

Activation of phospholipase C β by Gβγ and Gαq involves C-terminal rearrangement to release auto-inhibition

I. Fisher, M. L. Jenkins, G. G. Tall…·A. V. Smrcka

This study investigates how Gβγ and Gαq activate PLCβ by inducing structural changes in its C-terminal domain, leading to increased hydrolase activity.

DOI 10.1016/j.str.2020.04.012

protein structureexperimental assay

𝕏 PostBluesky