Cancer BiologybioRxivPreprint
Immunogenetic metabolomics revealed key enzymes that modulate CAR-T metabolism and function
P. A. Renauer, J. J. Park, M. Bai…·S. Chen
The paper identifies ADA as a metabolic regulator that enhances CAR-T cell function and tumor clearance through improved metabolism and reduced exhaustion.
DOI 10.1101/2023.03.14.532663