Cancer BiologybioRxiv
Prioritisation of oncology therapeutic targets using CRISPR-Cas9 screening
F. M. Behan, F. Iorio, E. Goncalves…·G. J. Mathew
This study uses CRISPR-Cas9 screens in cancer cell lines to identify and prioritize new oncology therapeutic targets based on gene fitness, biomarkers, and tractability.
DOI 10.1038/s41586-019-1103-9