Author

G. Lander

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:cryo-EM· 2 Research Focus:protein folding & dynamics· 2 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. de la Pena· 1 shared A. Hsu· 1 shared A. Sali· 1 shared D. A. Grotjahn· 1 shared J. Gestwicki· 1 shared K. Opoku-Nsiah· 1 shared M. Borgnia· 1 shared M. Wu· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

A. de la Pena

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3 papers

Recent·Most cited

The YPhi Motif Defines the Structure-Activity Relationships of Human 20S Proteasome Activators

J. Gestwicki, K. Opoku-Nsiah, A. de la Pena, S. K. Williams, N. Chopra, A. Sali, G. Lander

The paper identifies the Y-F/Y (Y{Phi}) motif as the human 20S proteasome recognition sequence, revealing structural and functional differences from archaeal systems.

bioRxiv · Apr 28, 2021Biochemistry

Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel

Y. Yin, M. Wu, A. Hsu, W. Borschel, M. Borgnia, G. Lander, S.-Y. Lee

This study reports cryo-EM structures of TRPM2 channel in intermediate states to elucidate structural transitions during ligand-dependent gating.

bioRxiv · Jan 9, 2019Biochemistry

Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility

D. A. Grotjahn, S. Chowdhury, Y. Xu, R. J. McKenney, T. Schroer, G. Lander

The paper uses cryo-electron tomography to reveal the 3D structure of the dynein-dynactin complex bound to microtubules, showing how dynactin recruits two dynein dimers for processive motility.

bioRxiv · Aug 31, 2017Cell Biology