Author

G. Parsonage

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. J. Beech· 2 shared L. Lichtenstein· 2 shared S. Futers· 2 shared C. Konstantinou· 1 shared C. W. Cheng· 1 shared E. A. V. Jones· 1 shared E. Chuntharpursat-Bon· 1 shared E. L. Evans· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersPhysiology

D. J. Beech

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

PIEZO1 force sensing controls global lipid homeostasis

L. Lichtenstein, C. W. Cheng, E. L. Evans, H. J. Gaunt, F. Bartoli, E. Chuntharpursat-Bon, S. Patel, C. Konstantinou, S. Futers, M. Reay, G. Parsonage, J. Bertrand-Michel, P. Sukumar, L. D. Roberts, D. J. Beech

This study shows that endothelial PIEZO1 force sensing regulates lipid homeostasis by affecting cholesterol metabolism and excretion, with implications for hyperlipidaemia.

bioRxiv · Jul 23, 2023 · PreprintPhysiology

Piezo1 channel activates ADAM10 sheddase to regulate Notch1 and gene expression

D. J. Beech, V. Caolo, M. Debant, N. Endesh, S. Futers, L. Lichtenstein, G. Parsonage, E. A. V. Jones

The paper shows that Piezo1 channels activate ADAM10 to regulate Notch1 cleavage and gene expression in response to mechanical force.

bioRxiv · Aug 12, 2019 · PreprintCell Biology