Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
L. M. Moser, N. Gogoberidze, A. Papaleo, A. Lucas, D. Dao, C. A. Friedrich, L. Paavolainen, C. Molnar, D. R. Stirling, J. Hung, R. Wang, C. Tromans-Coia, B. Li, E. L. Evans, K. W. Eliceiri, , B. A. Cimini
Piximi provides a no-programming web tool for biological image analysis using deep learning, enabling rapid insights without installation or coding.
bioRxiv · Jun 3, 2024 · PreprintCell Biology
G. A. Bertaccini, I. Casanellas, E. L. Evans, J. L. Nourse, G. D. Dickinson, G. Liu, S. Seal, A. T. Ly, J. R. Holt, T. D. Wijerathne, S. Yan, E. E. Hui, J. J. Lacroix, M. M. Panicker, S. Upadhyayula, , M. M. Pathak
This study uses HaloTag technology to visualize PIEZO1 localization and activity in hiPSC-derived cells and organoids, enabling mechanotransduction studies with high temporal resolution.
bioRxiv · Dec 22, 2023Biophysics
R. T. Behrens, J. K. Rajashekar, J. Bruce, E. L. Evans, A. M. Hansen, N. Salazar-Quiroz, L. M. Simons, P. Ahlquist, J. F. Hultquist, P. Kumar, N. M. Sherer
This paper edits human T cells to mimic rodent host factors, creating resistance to HIV-1 and related lentiviruses by disrupting key viral protein interactions.
mBio · Oct 31, 2023Peer-reviewedMicrobiology
L. Lichtenstein, C. W. Cheng, E. L. Evans, H. J. Gaunt, F. Bartoli, E. Chuntharpursat-Bon, S. Patel, C. Konstantinou, S. Futers, M. Reay, G. Parsonage, J. Bertrand-Michel, P. Sukumar, L. D. Roberts, D. J. Beech
This study shows that endothelial PIEZO1 force sensing regulates lipid homeostasis by affecting cholesterol metabolism and excretion, with implications for hyperlipidaemia.
bioRxiv · Jul 23, 2023 · PreprintPhysiology
J. Chen, J. R. Holt, E. L. Evans, J. S. Lowengrub, M. M. Pathak
This study investigates how PIEZO1 regulates leader cell formation and coordinated migration during keratinocyte wound healing, finding that PIEZO1 inhibits leader cell formation and disrupts coordinated directionality.
bioRxiv · Oct 13, 2022Biophysics
A. T. Ly, J. A. Freites, G. A. Bertaccini, E. L. Evans, G. D. Dickinson, D. J. Tobias, M. M. Pathak
This study uses single-particle tracking to show PIEZO1 exhibits heterogeneous diffusion in the plasma membrane, with mobility influenced by membrane composition and activation state.
bioRxiv · Sep 30, 2022Biophysics
J. R. Holt, W.-Z. Zeng, E. L. Evans, S.-H. Woo, S. Ma, H. Abuwarda, M. Loud, A. Patapoutian, M. M. Pathak
This study shows that PIEZO1 channel localization dynamics regulate keratinocyte migration and wound healing speed in mice.
bioRxiv · Oct 18, 2020Biophysics
J. T. Becker, E. L. Evans, B. E. Benner, S. L. Pritzl, L. E. Smith, A. E. Bates, N. M. Sherer
This study shows HIV-1 RNA interacts with APOBEC3G and MOV10 in the cytosol before Gag, and these interactions are critical for A3G packaging into virions.
bioRxiv · May 20, 2020 · PreprintCell Biology
N. M. Blythe, V. Stylianidis, M. J. Ludlow, H. T. Gilbert, E. L. Evans, K. Cuthbertson, R. Foster, J. Swift, J. Li, M. J. Drinkhill, F. A. van Nieuwenhoven, K. E. Porter, D. J. Beech, N. A. Turner
This study shows that activating Piezo1 channels in cardiac fibroblasts reduces myofibroblast differentiation and increases IL-6 secretion through Ca2+-dependent p38 MAP kinase activation.
bioRxiv · Apr 10, 2019Cell Biology