S. Kajimura

ZIP13 regulates lipid metabolism by changing intracellular iron and zinc balance

This study shows ZIP13 regulates lipid metabolism by modulating intracellular iron and zinc balance in adipocytes.

Sympathetic neuron-derived NPY protects from obesity by sustaining the mural progenitors of thermogenic adipocytes.

This study shows that sympathetic neuron-derived NPY sustains mural progenitors of thermogenic adipocytes, protecting against obesity by maintaining thermogenic capacity.

Mitochondrial choline import regulates purine nucleotide pools via SLC25A48

This study identifies SLC25A48 as a mitochondrial carrier that mediates choline import, regulating purine nucleotide synthesis and cell survival.

A liver-specific mitochondrial carrier that controls gluconeogenesis and energy expenditure

This study identifies SLC25A47 as a liver-specific mitochondrial carrier that regulates gluconeogenesis and energy expenditure by controlling pyruvate flux and FGF21 expression.

IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic Trypanosoma brucei infection

Metabolic flexibility via mitochondrial BCAA carrier SLC25A44 is required for optimal fever

This study identifies SLC25A44 as a mitochondrial BCAA carrier essential for metabolic flexibility and optimal fever response through enhanced mitochondrial BCAA oxidation and thermogenesis.