Author

G. Sim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

A. C. Kehling· 2 shared K. Nakanishi· 2 shared M. S. Park· 2 shared C. Divoky· 1 shared H. Min· 1 shared H. Zhang· 1 shared H.-J. Kim· 1 shared H.-Y. Kang· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

A. C. Kehling

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Determining the defining lengths between mature microRNAs/small interfering RNAs and tinyRNAs

G. Sim, A. C. Kehling, M. S. Park, C. Divoky, H. Zhang, N. Malhotra, J. Secor, K. Nakanishi

The paper determines the minimum guide lengths required for miR-20a and let-7a to maintain their RISC conformation, finding 19 and 20 nt respectively, and identifies 17-nt guides as functional tinyRNAs (tyRNAs) without PAZ domain anchoring.

bioRxiv · Oct 27, 2023Biochemistry

Label-free three-dimensional analyses of live cells with deep-learning-based segmentation exploiting refractive index distributions

J. Choi, H.-J. Kim, G. Sim, S. Lee, W. S. Park, J. H. Park, H.-Y. Kang, M. Lee, W. D. Heo, J. Choo, H. Min, Y. Park

The paper develops a label-free 3D segmentation method using deep learning to analyze live cells and their organelles without exogenous labels.

bioRxiv · May 23, 2021 · PreprintCell Biology

Human Argonaute2 and Argonaute3 are catalytically activated by different lengths of guide RNA

M. S. Park, G. Sim, A. C. Kehling, K. Nakanishi

The paper shows that 14-nt guide RNAs activate AGO3 as a slicer while inhibiting AGO2, revealing different optimal guide lengths for RNA cleavage by these Argonautes.

bioRxiv · Jul 16, 2020Biochemistry