ImmunologybioRxiv
Regnase-1 deficiency restrains Klebsiella pneumoniae infection by regulation of a Type I interferon response
G. Trevejo-Nunez, L. Fan, B. Lin…·S. Gaffen
This study shows that Regnase-1 deficiency increases resistance to Klebsiella pneumoniae infection by enhancing Type I interferon responses, despite not affecting bacterial clearance or pro-inflammatory cytokine expression.
DOI 10.1128/mbio.03792-21