H. Adachi

A root-specific NLR network confers resistance to plant parasitic nematodes

The paper identifies a root-specific NLR gene cluster in tomato that confers resistance to nematodes and evolved from an ancient NRC network.

The nucleotide binding domain of NRC-dependent disease resistance proteins is sufficient to activate downstream helper NLR oligomerization and immune signaling

The NRC0 gene cluster of sensor and helper NLR immune receptors is functionally conserved across asterid plants

The paper investigates the functional conservation of the NRC0 gene cluster across asterid plants and shows its role in immune responses.

Discrimination of SARS-CoV-2 Omicron sub-lineages BA.1 and BA.2 using a high-resolution melting-based assay: A pilot study

This study develops a high-resolution melting assay to distinguish SARS-CoV-2 Omicron sub-lineages BA.1 and BA.2 using mutation patterns in the spike protein with 100% sensitivity and >97.5% specificity.

Considering decoupled phenotypic diversification between ontogenetic phases in macroevolution: An example using Triggerfishes (Balistidae)

The paper examines ontogenetic variation in locomotor morphology of triggerfishes, revealing decoupled diversification dynamics between adult and juvenile stages.

An atypical NLR protein modulates the NRC immune receptor network

The paper identifies NRCX, an atypical NRC family member, and shows it modulates the NRC immune receptor network by affecting plant growth and hypersensitive responses.

The helper NLR immune protein NRC3 mediates the hypersensitive cell death caused by the cell-surface receptor Cf-4

The paper identifies NRC3 as an NLR protein required for hypersensitive cell death triggered by the PRR Cf-4 in response to the fungal effector Avr4.

Rpi-amr3 confers resistance to multiple Phytophthora species by recognizing a conserved RXLR effector

The paper identifies Rpi-amr3 as a resistance gene that recognizes a conserved RXLR effector from multiple Phytophthora species, conferring broad resistance.

Dynamic accumulation of a helper NLR at the plant-pathogen interface underpins pathogen recognition

This study shows that the NLR protein NRC4 dynamically changes its subcellular localization during plant-pathogen interaction, accumulating at the haustorium interface before activation and redistributing after immune recognition.

Plant pathogens convergently evolved to counteract redundant nodes of an NLR immune receptor network

The paper identifies effectors from plant pathogens that specifically target subsets of NRC immune receptor proteins, revealing convergent strategies to counteract redundant nodes in the NLR network.

Jurassic NLR: conserved and dynamic evolutionary features of the atypically ancient immune receptor ZAR1

This study reconstructs the evolutionary history of the ancient ZAR1 NLR immune receptor, revealing conserved features and novel domain acquisitions across plant lineages.

RefPlantNLR: a comprehensive collection of experimentally validated plant NLRs

The paper introduces RefPlantNLR, a dataset of 442 experimentally validated plant NLRs, and benchmarks NLR annotation tools, leading to the development of a new pipeline, NLRtracker.

A vector system for fast-forward in vivo studies of the ZAR1 resistosome in the model plant Nicotiana benthamiana

The paper introduces a vector system of 52 plasmids for studying the ZAR1 resistosome in Nicotiana benthamiana, confirming NbZAR1 as the ortholog and demonstrating its functional properties.

A complex resistance locus in Solanum americanum recognizes a conserved Phytophthora effector

The paper identifies a new R gene, Rpi-amr1, from Solanum americanum that provides broad-spectrum resistance to Phytophthora infestans and defines its allelic diversity.

A CRISPR/Cas9 mediated 53 kb deletion of the NRC4 gene cluster of tomato does not affect bacterial flagellin-triggered immunity

This study deletes the NRC4 gene cluster in tomato using CRISPR/Cas9 and finds it does not affect flg22-induced immunity.

An N-terminal motif in NLR immune receptors is functionally conserved across distantly related plant species

The paper identifies a conserved N-terminal motif in plant NLR immune receptors and shows its functional conservation across species.