Author
J. M. Harris
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2020-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 39 mutual co-author links6 papers
Recent·Most cited
- MicrobiologybioRxivPreprint
Circadian regulation of human immunodeficiency virus type 1 replication
H. Borrmann, G. Ulkar, A. E. Kliszczak…·J. A. McKeating
This study shows HIV-1 replication is regulated by circadian rhythms through interactions between transcription factors BMAL1, REV-ERB, and ROR, with implications for HIV therapy.
DOI 10.1101/2022.11.30.518024 - MicrobiologybioRxiv
Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model.
P. A. Wing, M. Prange-Barczynska, A. Cross…·J. A. McKeating
This study shows that activating HIF signaling reduces SARS-CoV-2 infection and respiratory symptoms in hamsters by decreasing viral RNA and epithelial damage.
DOI 10.1371/journal.ppat.1010807 - MicrobiologybioRxiv
The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells
X. Zhuang, S. Tsukuda, F. Wrensch…·J. A. McKeating
This study shows BMAL1 regulates ACE2 expression and SARS-CoV-2 entry in lung epithelial cells, with SR9009 reducing viral replication through circadian mechanisms.
DOI 10.1016/j.isci.2021.103144 - MicrobiologyCellular MicrobiologyPeer-reviewed
The CCCTC-binding factor CTCF represses hepatitis B virus Enhancer I and regulates viral transcription
V. D'Arienzo, J. Ferguson, G. Giraud…·J. L. Parish
This study identifies CTCF as a repressor of HBV transcription by binding to Enhancer I and reducing pre-genomic RNA levels.
- MicrobiologybioRxiv
Hypoxic gene expression in chronic hepatitis B infected patients is not observed in state-of-art in vitro and mouse infection models
P. J. Liu, J. M. Harris, E. Marchi…·J. A. McKeating
The paper shows hypoxia gene upregulation in chronic hepatitis B patients is not observed in in vitro or mouse models, suggesting inflammatory factors may drive this effect.