BiochemistrybioRxiv
The carboxyl-terminal sequence of Bim enables Bax activation and killing of unprimed cells
X. Chi, J. Pemberton, D. Nguyen…·D. Andrews
This study shows that the carboxyl-terminal sequence of Bim is necessary for Bax activation and cell killing, independent of anti-apoptotic protein inhibition.
DOI 10.7554/elife.44525